Exercise Capacity According to Coronary Microvascular Dysfunction and Body Composition
Recruiting · NCT04822649 · Interventional (participants receive a specific treatment) · Lead sponsor: Korea University Anam Hospital
View the official record on ClinicalTrials.gov →Interventions studied
Adenosine stress echocardiography with the evaluation of coronary artery blood flow
What this trial is about
The correlation of coronary microvascular function and body composition with cardiopulmonary exercise capacity will be assessed in patients with heart failure with preserved ejection fraction.
Who can take part
Age range
20 Years to 80 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Age 20 to 80
- Typical/atypical chest pain or ischemic symptoms including dyspnea
- No significant coronary artery stenosis (\>50% stenosis) in coronary angiography or computed tomography
- Left ventricular ejection fraction ≥50%
Exclusion criteria
- More than moderate valvular heart disease
- Congenital heart disease
- Chronic renal failure (estimated glomerular filtration rate \<30 ml/min/1.73m2) or end-stage renal failure undergoing hemodialysis or peritoneal dialysis
- Asthma, chronic obstructive pulmonary disease and primary pulmonary hypertension
- Receiving anticancer drugs
- Vasculitis associated with autoimmune diseases
- Patients with difficulty in performing exercise load evaluation (treadmill, bicycle ergometer)
- Atrial fibrillation
- Atrioventricular block with more than second degrees, symptomatic bradycardia, cryo-node failure syndrome, Wolff-Parkinson-White (WPW) patients
Where it is running
1 location listed.
- Korea University Anam Hospital - Seoul, South Korea