Bilateral Lateral OFC rTMS in Obsessive Compulsive Disorder
Recruiting · NCT04934007 · Interventional (participants receive a specific treatment) · Lead sponsor: Centre Hospitalier Henri Laborit
View the official record on ClinicalTrials.gov →Interventions studied
rTMS Treatment
What this trial is about
According to the literature the lateral part of the Orbito Frontal Cortex (lOFC) is a relevant bilateral target for repetitive Trans-cranial Magnetic Stimulation (rTMS) in Obsessive Compulsive Disorder (OCD). Both hemispheres are concerned in terms of target.
Who can take part
Age range
18 Years to 65 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Age: Participants will be both males and females, 18-65 years of age included.
- diagnosis of OCD
- all the patients must have failed to respond to at least two different pharmacological treatment used for at least 6 weeks
- Affiliation to a social security system (recipient or assignee),
- Signed written inform consent form
Exclusion criteria
- The exclusion criteria are a diagnosis of another psychiatric disorder (except for anxious disorders), a diagnosis of a significant active medical illness, pregnancy or other neurological illness
- In accordance with the safety criteria for rTMS, patients with a history of seizure or bearing pacemakers, mobile metal implants, implanted medical pumps, or metal clips placed inside the skull will also be excluded
- The patients won't be allowed to change their medication during the trial. The treatment must be stable at least 3 week before day 0.
- Female subject who is pregnant, or of child-bearing age, sexually active and not using reliable contraception or who is nursing,
- Patient under curators
- Patient hospitalized under duress
- Patient unable to give his or hers informed consent
Where it is running
2 locations listed.
- Sorbonne University, Pitié-Salpêtrière Hospital - Paris, France
- Centre Hospitalier Henri Laborit - Poitiers, France