Parkinson's Foundation PD GENEration Genetic Registry
Recruiting · NCT04994015 · Observational (researchers observe without assigning treatment) · Lead sponsor: Parkinson's Foundation
View the official record on ClinicalTrials.gov →Interventions studied
Lab Assay for seven genetic variants for Parkinson's Disease
What this trial is about
Development of a central repository for PD-related genomic data for future research.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Study Population 1: PWP (open for recruitment)
- Meet Movement Disorder Society (MDS) Clinical Diagnostic Criteria for Parkinson's Disease: probable diagnosis.
- Willingness to undergo genetic testing, and choose to be informed of genetic testing results for GBA, LRRK2 and 5 additional PD related genes (SNCA, VPS35, PRKN, PINK-1, PARK7).
- Capacity to give full informed consent in writing or electronically, and have read and signed the informed consent forms (ICFs) based on site clinician's determination.
- Able to perform study activities (including completion of either online, in-person or paper surveys).
- Study Population 2: People at risk of developing PD (not open for recruitment)
- \. Family members of Study Population 1 may be invited to participate in the study if confirmatory genetic testing is deemed necessary by the genetic testing laboratory.
Exclusion criteria
- Diagnosis of an atypical parkinsonian disorder (i.e., multiple system atrophy, progressive supranuclear palsy, dementia with Lewy bodies, corticobasal syndrome), including that due to medications, metabolic disorders, encephalitis, cerebrovascular disease, or normal pressure hydrocephalus.
- Individuals who have received a blood transfusion within the past 3 months.
- Individuals who have active hematologic malignancies such as lymphoma or leukemia.
- Individuals who have had a bone marrow transplant within the past 5 years.
- Under the age of 18
Where it is running
60 locations listed across 35 US states.
- University of Alabama Birmingham - Birmingham, Alabama, United States
- MD First Research - Chandler, Arizona, United States
- Barrow Neurological Institute - Phoenix, Arizona, United States
- University of Arkansas - Fayetteville, Arkansas, United States
- University of California San Diego (UCSD) - La Jolla, California, United States
- University of Southern California - Los Angeles, California, United States
- University of California Los Angeles - Los Angeles, California, United States
- Stanford University - Redwood City, California, United States
- University of California San Francisco (UCSF) - San Francisco, California, United States
- University of Colorado Anschutz - Aurora, Colorado, United States
- University of Connecticut - Farmington, Connecticut, United States
- Hartford Healthcare - Hartford, Connecticut, United States
- Aventura Neurology - Visionary Investigators Network - Aventura, Florida, United States
- Parkinson's Disease & Movement Disorder Center of Boca Raton - Boca Raton, Florida, United States
- University of Florida - Gainesville, Florida, United States
- University of Miami - Miami, Florida, United States
- Cleveland Clinic Weston - Weston, Florida, United States
- Morehouse College - Atlanta, Georgia, United States
- The Queen's Health System - Honolulu, Hawaii, United States
- University of Illinois-Chicago - Chicago, Illinois, United States
- Rush University - Chicago, Illinois, United States
- University of Chicago - Chicago, Illinois, United States
- Northwestern University - Evanston, Illinois, United States
- Indiana University - Indianapolis, Indiana, United States
- University of Iowa - Iowa City, Iowa, United States
- University of Kansas - Lawrence, Kansas, United States
- University of Kentucky - Lexington, Kentucky, United States
- Louisiana State University - Shreveport, Louisiana, United States
- Maine Medical Center - Portland, Maine, United States
- Johns Hopkins - Baltimore, Maryland, United States
- University of Maryland - College Park, Maryland, United States
- Massachusetts General Hospital (MGH) - Boston, Massachusetts, United States
- BMC Community Hospital - Boston, Massachusetts, United States
- Beth Israel Deaconess Medical Center (BIDMC) - Boston, Massachusetts, United States
- University of Michigan - Ann Arbor, Michigan, United States
- Struthers Parkinson's Center - HealthPartners Park Nicollet - Golden Valley, Minnesota, United States
- Cleveland Clinic Lou Ruvo Center for Brain Health - Las Vegas, Nevada, United States
- Rutgers University - New Brunswick, New Jersey, United States
- University of New Mexico - Albuquerque, New Mexico, United States
- New York University - New York, New York, United States
- Mount Sinai - New York, New York, United States
- Columbia University - New York, New York, United States
- University of Rochester Medical Center - Rochester, New York, United States
- University of North Carolina - Chapel Hill - Chapel Hill, North Carolina, United States
- Atrium Health - Charlotte, North Carolina, United States
- University of Cincinnati - Cincinnati, Ohio, United States
- Case Western Reserve University - Cleveland, Ohio, United States
- Cleveland Clinic - Cleveland, Ohio, United States
- Ohio State University - Colombus, Ohio, United States
- Oregon Health and Science University - Portland, Oregon, United States
- University of Pennsylvania - Philadelphia, Pennsylvania, United States
- Thomas Jefferson University - Philadelphia, Pennsylvania, United States
- Allegheny Health Network - Pittsburgh, Pennsylvania, United States
- Medical University of South Carolina - Charleston, South Carolina, United States
- Vanderbilt University - Nashville, Tennessee, United States
- Baylor College of Medicine - Houston, Texas, United States
- The University of Texas Health Science Center at Houston - Houston, Texas, United States
- University of Texas at San Antonio - San Antonio, Texas, United States
- Intermountain Health - Murray, Utah, United States
- Virginia Commonwealth University - Richmond, Virginia, United States
Showing 60 of 70 listed sites. See the official record for the complete list.
Read the full protocol, contacts and eligibility on ClinicalTrials.gov →