Understanding Motivation in Parkinson's Patients Through Neurophysiology
Recruiting · NCT05065151 · Interventional (participants receive a specific treatment) · Lead sponsor: University of California, San Francisco
View the official record on ClinicalTrials.gov →Interventions studied
Decision Making TaskStimulation offStimulation on
What this trial is about
The study aims to better understand motivation and value-based decision-making in Parkinson's patients through neurophysiology using Medtronic's Percept DBS device. By combining behavioral tasks with neural recordings, the study seeks to uncover how DBS affects motivation, particularly in relation to effort, reward, and timing.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Has Parkinson's Disease or Dystonia
- Has Medtronic Percept or RC+S DBS device implanted in either GPI or STN
- Has DBS device implanted either bilaterally or unilaterally
- Male or female
- More than 1 month post-DBS surgery
Exclusion criteria
- Severe cognitive impairments
- Has MOCA score below 20
- Pregnancy
- Age less than 18 years old
Where it is running
1 location listed across 1 US state.
- University of California San Francisco - San Francisco, California, United States