A Retrospective Protocol Empowering Precision Research in Colorectal Cancer (ALFAOMEGA-RETRÒ)
Recruiting · NCT05101382 · Observational (researchers observe without assigning treatment) · Lead sponsor: IFOM ETS - The AIRC Institute of Molecular Oncology
View the official record on ClinicalTrials.gov →Interventions studied
Observation
What this trial is about
ALFAOMEGA-RETRÒ will be exploited to retrospectively collect clinical and imaging data and archival samples to be used for validation and correlative studies on markers discovered by cutting-edge translational projects within the AIRC5x1000 program "Insights into the evolving heterogeneity of colorectal cancer (CRC): from mechanism to therapies" (an ongoing multi-institutional research program).
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Histologically-confirmed diagnosis of colorectal cancer (any stage).
- Age \>18 years at the time of diagnosis.
- Availability of clinically-annotated radio-imaging data and/or diagnostic Formalin-Fixed Paraffin Embedded (FFPE) blocks (surgical resections and/or tumor biopsies), or at least 10 slides (preferably 20). FFPE tissue blocks are always preferred to slides.
- Verification that the patient could not be reached for informed consent in accordance with applicable national regulations.
Exclusion criteria
- if inclusion criteria are not met
Where it is running
13 locations listed.
- Hospital del Mar - Parc de Salut Mar - Barcelona, Spain
- Vall d'Hebron Institute of Oncology (VHIO) - Barcelona, Spain
- INCLIVA - Instituto de Investigatión Sanitaria - Valencia, Spain
- Institut Català D'Oncologia (ICO) - L'Hospitalet de Llobregat, Barcelona, Spain
- Ospedale Policlinico San Martino - Genova, GE, Italy
- Fondazione IRCCS, Istituto Nazionale dei Tumori - Milan, MI, Italy
- Niguarda Cancer Center - ASST Grande Ospedale Metropolitano Niguarda - Milan, MI, Italy
- IRCCS Istituto Clinico Humanitas - Milan, MI, Italy
- Istituto Oncologico Veneto (IOV) - Padua, PD, Italy
- Azienda Ospedaliero Universitaria Pisana - Pisa, Pisa, Italy
- Istituto di Candiolo - IRCCS - Candiolo, TO, Italy
- Azienda Ospedaliero Universitaria San Luigi Gonzaga - Orbassano, TO, Italy
- Azienda Ospedaliera Ordine Mauriziano - Torino, TO, Italy