Tempus CRC Surveillance Study: A ctDNA Biomarker Profiling Study of Patients With CRC Using NGS Assays
Recruiting · NCT05234177 · Observational (researchers observe without assigning treatment)
View the official record on ClinicalTrials.gov →Interventions studied
Observation
What this trial is about
The study is an observational multicenter evaluation of participants with colorectal cancer (CRC) who will receive longitudinal plasma ctDNA biomarker profiling in addition to their standard-of-care therapy and disease surveillance.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Known or suspected colorectal adenocarcinoma (Stage I to IVA disease)
- Planning to undergo or has undergone a surgical resection for suspected adenocarcinoma of the colon or rectum with curative intent.
- 18 years old or older
- Willing and able to provide informed consent
- Willing to have additional blood samples collected during routine surveillance visits
Exclusion criteria
- Not willing to have additional blood samples collected
- Pathology that is not consistent with colorectal adenocarcinoma
Where it is running
20 locations listed across 12 US states.
- Mercy Clinic Oncology - Fort Smith - Fort Smith, Arkansas, United States
- MemorialCare - Fountain Valley, California, United States
- The Center for Cancer and Blood Disorders - Bethesda, Maryland, United States
- Mercy Clinic Oncology and Hematology - Joplin - Joplin, Missouri, United States
- Mercy Clinic Cancer and Hematology - Chub O'Reilly Cancer Center - Springfield, Missouri, United States
- Washington University School of Medicine - St Louis, Missouri, United States
- Mercy Clinic Oncology and Hematology - Sindelar Cancer Center - St Louis, Missouri, United States
- Mercy Clinic Oncology and Hematology - David C. Pratt Cancer Center - St Louis, Missouri, United States
- Nebraska Cancer Specialists - Omaha, Nebraska, United States
- Southeastern Medical Oncology Center - Goldsboro, North Carolina, United States
- Aultman Hospital - Canton, Ohio, United States
- TriHealth Cancer Institute - Cincinnati, Ohio, United States
- Ohio State University - Columbus, Ohio, United States
- OhioHealth Research Institute - Columbus, Ohio, United States
- Toledo Clinic Cancer Center - Toledo, Ohio, United States
- Mercy Clinic Oncology and Hematology - Coletta - Oklahoma City, Oklahoma, United States
- Cancer Care Associates of York - York, Pennsylvania, United States
- Utah Cancer Specialists - Salt Lake City, Utah, United States
- University of Washington / Fred Hutchinson Cancer Center - Seattle, Washington, United States
- ThedaCare Regional Cancer Center - Appleton, Wisconsin, United States