Early Treatment of Atrial Fibrillation for Stroke Prevention Trial in Acute STROKE
Recruiting · NCT05293080 · Interventional (participants receive a specific treatment) · Lead sponsor: Universitätsklinikum Hamburg-Eppendorf
View the official record on ClinicalTrials.gov →Interventions studied
Medical or interventional therapy for rhythm control in atrial fibrillation (antiarrhythmic drugs, ablation, electric cardio version)Usual care for atrial fibrillation
What this trial is about
This study will determine whether early, comprehensive, rhythm control therapy prevents adverse cardiovascular outcome in patients with acute ischemic stroke and atrial fibrillation compared to usual care.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Phase 3
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Acute ischemic stroke in the previous four weeks, diagnosed by imaging (CT or MRI) or clinical diagnosis
- Possibility to start the trial treatment within 4 weeks after stroke, and as soon as clinically justifiable
- AF first detected ≤1 year prior to randomization
- Informed consent
Exclusion criteria
- End-stage cancer or life-expectancy \< 12 months due to other advanced co-morbid illness
- Prior AF ablation or surgical therapy of AF
- Patients not suitable for rhythm control of AF due to cardiac conditions
Where it is running
1 location listed.
- University Medical Center Hamburg-Eppendorf - Hamburg, Germany