Real-time fMRI Neurofeedback in Patients With Schizophrenia and Auditory Hallucinations
Recruiting · NCT05299749 · Interventional (participants receive a specific treatment) · Lead sponsor: Boston VA Research Institute, Inc.
View the official record on ClinicalTrials.gov →Interventions studied
sham-rt-fMRI-Neurofeedbackstg-rt-fMRI-Neurofeeback
What this trial is about
Neurofeedback intervention aimed to regulate the superior temporal gyrus (STG) activation and default mode network (DMN) connectivity as well as to reduce the auditory hallucinations (AH) schizophrenia patients with medication resistant AH.
Who can take part
Age range
18 Years to 55 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- patients diagnosed with SZ or schizoaffective disorder using DSM-5 criteria
- auditory hallucinations not responsive to pharmacology as determined by chart review and a clinical interview of SCID.
Exclusion criteria
- neurologic illness
- major head trauma
- electroconvulsive therapy
- alcohol or drug dependence
- alcohol or drug abuse within the past five years
- verbal IQ below 70
Where it is running
1 location listed across 1 US state.
- Boston VA Healthcare System, Brockton - Brockton, Massachusetts, United States