Non-invasive Neurostimulation as a Tool for Diagnostics and Management for Neurodegenerative Diseases
Recruiting · NCT05326750 · Interventional (participants receive a specific treatment) · Lead sponsor: Kuopio University Hospital
View the official record on ClinicalTrials.gov →Interventions studied
Gamma tACS (40 Hz) over the superior parietal cortex
What this trial is about
Double blinded, sham-controlled, randomized trial on repeated transcranial alternating current brain stimulation (tACS) in neurodegenerative diseases. The investigators will evaluate whether a 4-times daily repeated stimulation with gamma tACS on the posterior parietal cortex can improve symptoms in patients with neurodegenerative diseases, including dementia with Lewy Bodies, Alzheimer's disease, idiopathic normal pressure hydrocephalus and Frontotemporal dementia.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Mild Cognitive Impairment due to Alzheimer's disease
- Dementia with Lewy Bodies
- Frontotemporal dementia
- Idiopathic normal pressure hydrocephalus (iNPH)
Exclusion criteria
- History of seizures
- Pregnancy
- Metal implants in the head (except dental fillings)
- Electronic implants (i.e. pace-maker, implanted medical pump)
- Age \<18 years
Where it is running
1 location listed.
- Kuopio University Hospital - Kuopio, Finland