Using Transcranial Magnetic Stimulation (TMS) to Understand Hallucinations in Schizophrenia
Recruiting · NCT05343598 · Interventional (participants receive a specific treatment) · Lead sponsor: Mclean Hospital
View the official record on ClinicalTrials.gov →Interventions studied
Repetitive Transcranial Magnetic Stimulation (rTMS)Sham Repetitive Transcranial Magnetic Stimulation (rTMS)
What this trial is about
This study uses a noninvasive technique called transcranial magnetic stimulation (TMS) to study how hallucinations work in schizophrenia. TMS is a noninvasive way of stimulating the brain, using a magnetic field to change activity in the brain. The magnetic field is produced by a coil that is held next to the scalp. In this study the investigators will be stimulating the brain to learn more about how TMS might improve these symptoms of schizophrenia.
Who can take part
Age range
18 Years to 55 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Diagnosis of schizophrenia or schizoaffective disorder
Exclusion criteria
- substance use disorder in past 3 months
- ambidexterity
- contraindications for TMS or MRI including :
- history of neurological disorder
- history of head trauma resulting in loss of consciousness
- history of seizures or diagnosis of epilepsy or first degree relative family history of epilepsy
- metal in brain or skull
- implanted devices such as a pacemaker, medication pump, nerve stimulator or ventriculoperitoneal shunt
- claustrophobic in MRI
Where it is running
1 location listed across 1 US state.
- McLean Hospital - Belmont, Massachusetts, United States