Extracellular Vesicles and Particles (EVP) as Biomarkers of Recurrence in Non-Small Cell Lung Cancer
Recruiting · NCT05424029 · Observational (researchers observe without assigning treatment) · Lead sponsor: Memorial Sloan Kettering Cancer Center
View the official record on ClinicalTrials.gov →What this trial is about
The purpose of this study is to find out if fluid rinsed from peoples' airways (bronchial washing samples) during routine surgery to remove (resect) their non-small cell lung cancer (NSCLC) tumors contains enough vesicles to do testing that may help the researchers learn more about their NSCLC.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- All patients ≥ 18 years of age undergoing consideration of surgical resection, including lobar resections, sublobar resections, and pneumonectomies, for primary lung cancer will be eligible.
- Patients with previously resected disease and/or previous radiation therapy will be considered on a case by case basis.
Exclusion criteria
- Patients with active infection or pneumonia which may impact exosome makeup
- Additionally, if at the discretion of the operating surgeon, obtaining bronchial washings would lead to undue morbidity, the patient would be excluded and replaced
Where it is running
7 locations listed across 2 US states.
- Memorial Sloan Kettering Basking Ridge (Consent Only) - Basking Ridge, New Jersey, United States
- Memorial Sloan Kettering Monmouth (Consent Only) - Middletown, New Jersey, United States
- Memorial Sloan Kettering Bergen (Consent Only) - Montvale, New Jersey, United States
- Memorial Sloan Kettering Suffolk - Commack (Consent Only) - Commack, New York, United States
- Memorial Sloan Kettering Westchester (Consent Only) - Harrison, New York, United States
- Memorial Sloan Kettering Cancer Center - New York, New York, United States
- Memorial Sloan Kettering Nassau (Consent Only) - Uniondale, New York, United States