A Multicenter Cohort Study on Maternal and Infant Microecology and New Targets for Pre-eclampsia Screening in China
Recruiting · NCT05445544 · Observational (researchers observe without assigning treatment) · Lead sponsor: Zhujiang Hospital
View the official record on ClinicalTrials.gov →Interventions studied
Observational studies, The diagnosis was preeclampsia
What this trial is about
major objective This multicenter, prospective cohort study aims at evaluating the predictive value of microbiome ,proteomics and serum markers in preeclampsia. secondary objective to evaluate the value of microbiome,proteomics and serum markers in assessing pregnancy outcome (complications during pregnancy and delivery, delivery) and neonatal prognosis.
Who can take part
Age range
18 Years and older
Sex
Female
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Aged \>=18 years;
- Pregnancy woman;
- With a singleton pregnancy;
- Volunteer and receive regular antenatal examinations in the research centers;
- Volunteer to sign a written informed consent.
Exclusion criteria
- Concurrent with hypertension, diabetes, liver and kidney diseases, hematonosis and other serious diseases of pre-pregnancy women, including patients requiring long-term medication for primary diseases;
- With history of preeclampsia;
- Tumor patients concurrent with serious infection requiring long-term drug treatment;
- Pregnant women conceiving through in vitro fertilization;
- Multiple pregnancies;
- Patients with clear indications of medical pregnancy termination during early pregnancy;
- Any medical or non-medical conditions deemed inappropriate for study participation according to the investigator.
Where it is running
2 locations listed.
- Zhujiang Hospital of Southern Medical University - Guangzhou, Guangdong, China
- Zhujiang hospital - Guangzhou, Guangdong, China