Inspiratory Muscle Strength Training in Adults With Obesity

Recruiting · NCT05459636 · Interventional (participants receive a specific treatment) · Lead sponsor: Florida State University

Interventions studied

High-resistance inspiratory muscle strength trainingVery-low-resistance inspiratory muscle strength training

The purpose of this study is to determine whether inspiratory muscle strength training reduces blood pressure in adults with obesity.

Age range

18 Years to 45 Years

Sex

All (male and female)

Healthy volunteers

Yes - healthy volunteers may be accepted

Phase

Not applicable (e.g. observational or device study)

Study type

Interventional (participants receive a specific treatment)

Not weight stable (\<5% change in body mass over the past six months)
Overt cardiovascular, neurological, renal, liver, and/or metabolic illness (e.g., diabetes mellitus)
Current, or history of uncontrolled, Stage 2 hypertension (blood pressure \>140 / 90 mmHg; anti-hypertensive medications are permitted)
Diagnosed obstructive sleep apnea
Previous bariatric surgery
Diagnosis or signs (e.g., values below the lower limit of normal) of overt airway disease(s)
Current or recent (regular use within the past 6 months) use of tobacco or nicotine products (e.g., cigarettes, vaping)
Pregnant (self-reported and confirmed via urine pregnancy test), lactating (self-reported), or post-menopausal (self-reported) females
Prisoners
Per the POWERbreathe® company:
Patients who have undergone recent abdominal surgery and those with abdominal hernia.
Asthma patients who have a very low symptom perception and suffer from frequent, severe exacerbations or with an abnormally low perception of dyspnea.
If a patient is suffering from a ruptured eardrum or any other condition of the ear.
Patients with marked elevated left ventricular end-diastolic volume and pressure.
Patients with worsening heart failure signs and symptoms after training.
If an individual is suffering from a cold, sinusitis or respiratory tract infection, it is advised that they do not use the POWERbreathe device.

1 location listed across 1 US state.