Treatment Preventive for Pre-eclampsia by Acetylsalicylic Acid in Women Who Underwent Frozen Embryo Transfer
Recruiting · NCT05460416 · Interventional (participants receive a specific treatment) · Lead sponsor: Centre Hospitalier Universitaire de Liege
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
Title: A prospective multicentric interventional randomized controlled trial to assess the effect of low dose acetylsalicylic acid as a preventive treatment of pre-eclampsia in pregnant women who underwent frozen embryo transfer
Who can take part
Age range
18 Years to 43 Years
Sex
Female
Healthy volunteers
No - a diagnosis or condition is required
Phase
Phase 3
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Healthy women from \[18 - 43\] years-old, planned for a frozen embryo transfer, with natural and modified natural or HRT cycle
- Who have given their informed consent
- Who have a confirmed pregnancy at week 6 of amenorrhea.
Exclusion criteria
- Women presenting one risk factor for preeclampsia: multiple pregnancy, history of preeclampsia, BMI \> 30, lupus syndrome, preexistent proteinuria, non-treated chronic high blood pressure (\>140/90), antiphospholipid antibody syndrome, diabetes (fasting blood sugar \>126mg/dl)
- Contraindication to acetylsalicylic acid (at risk of active hemorrhage (like hemophilia, …); at risk of or who have a gastro-duodenal ulcer; at risk or how have a terminal renal or hepatic in-sufficiency (only if acetylsalicylic acid is given at high dose)
- Already treated with acetylsalicylic acid
- Treatment with anticoagulants or non-steroid anti-inflammatory drugs
Where it is running
1 location listed.
- Centre Hospitalier Universitaire de Liège site Citadelle - Liège, Belgium