Lung Nodule Detection Using Ultra-long FOV PET/CT
Recruiting · NCT05463913 · Interventional (participants receive a specific treatment) · Lead sponsor: University Medical Center Groningen
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
Indeterminate lung nodules (6-15mm) are frequent findings in patients undergoing chest CT scanning, but adequate follow-up imaging is currently not in place to facilitate early detection, diagnosis and decision making regarding treatment. The introduction of long Field-Of-View PET/CT scanners could make a difference in this matter due to the substantial increase in sensitivity allowing optimal image quality. Whether this new technology could provide improved detection and follow-up of indeterminate lung nodules is what we aim to explore in this study.
Who can take part
Age range
18 Years to 100 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Phase 4
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- able to give informed consent
- signed informed consent
- confirmed indeterminate lung nodule(s) of 6-15 mm in size on CT chest imaging
- routine 18F-FDG PET/CT performed
- scheduled for biopsy or resection of the lung nodules
Exclusion criteria
- claustrophobia
- pregnant or breastfeeding
- interval of at least 2 weeks between PET scan and last date of systemic anti-cancer therapy to reduce false-negative uptake in lesions
- radiation therapy of the target lung nodule(s)
- uncontrolled diabetes mellitus
- any medical condition potentially hampering conduction of the trial
Where it is running
1 location listed.
- University Medical Center Groningen - Groningen, Netherlands