Biobank and Register of Patients With Agresive Tumors for Translational and Analytical Research
Recruiting · NCT05539677 · Observational (researchers observe without assigning treatment) · Lead sponsor: N.N. Petrov National Medical Research Center of Oncology
View the official record on ClinicalTrials.gov →What this trial is about
The investigators will collect biosamples of patient blood and tumour tissue for further immunological analysis of blood cell subpopulations, immunosupressive factors concentration, HLA expression an lymphocytes and tumour tissue, and and cancer testis antigenes expression on tumour cells, as well as clinical data on patient's stage, therapy, response and demographics. Possible prognostic and predictive dynamic biomarkers will be discovered for individualisation of treatment strategies
Who can take part
Age range
1 Year and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Signed inform consent
- Histolgically verified solid tumour
- Receiving systemic therapy for neoplasm
- Has archival tumour tissue
- Provide biosamples with living tumour tissue or blood samples for immunologic assessment
Exclusion criteria
- Concurrent Lymphoprolipherative disorder
- Patients after stem cell or bone marrow thansplantation
- Incomplete informaton on previous cancer history or medical history
- Patients with known primary immunodeficiency
- Patients receiving immunosupressive therapy for concurrent illness
- Pregnant patients
Where it is running
1 location listed.
- N.N. Petrov NMRC of Oncology, Oncoimmunology dep. - Saint Petersburg, Russia