Micro-doses of Physical Activity for COPD

Recruiting · NCT05553223 · Interventional (participants receive a specific treatment) · Lead sponsor: University of British Columbia

View the official record on ClinicalTrials.gov →

COPD Hypertension

Interventions studied

Microdoses of activity

What this trial is about

Chronic obstructive pulmonary disease (COPD) is a disease of the lungs that makes it hard for people to breath. Those with COPD spend considerably more time sitting and lying and less time performing physical activity than healthy individuals. Those who are the most sedentary have a greater risk of heart and blood vessel disease, which may lead to an early death. This project will investigate the effect of sitting still for 3 hours on blood vessel health in individuals with COPD. It will also investigate whether breaking up the amount of time patients sit with regular short bouts of walking (5 minutes each hour) at a comfortable pace chosen by the patient can have a positive effect on maintaining the health of their blood vessels. It is hypothesized that blood vessel health will be worse after 3 hours of sitting compared to when the sitting is broken up by short bouts of walking.

Who can take part

Age range

No age limits stated

Sex

All (male and female)

Healthy volunteers

No - a diagnosis or condition is required

Phase

Not applicable (e.g. observational or device study)

Study type

Interventional (participants receive a specific treatment)

Inclusion criteria

Non-smoking (\>6 months) patients with stable moderate-to-severe COPD (post bronchodilator forced expired volume in 1 sec/forced vital capacity\<0.7 and \<lower limit of normal, 30%\<Forced Expired Volume in 1 sec\<80% predicted and exacerbation free for \>6 weeks) will be recruited for the study.

Exclusion criteria

performing structured exercise training (or pulmonary rehabilitation)
have a history of deep vein thrombosis
are on anticoagulant medication
have advanced cardiac or cerebrovascular disease (i.e. heart failure, previous stroke or myocardial infarction)
have diabetes
have musculoskeletal contraindications that limit their ability to perform physical activity
vascular ultrasound measurements cannot be obtained.

Where it is running

1 location listed.

University of British Columbia - Kelowna, British Columbia, Canada

Read the full protocol, contacts and eligibility on ClinicalTrials.gov →