Global Blood-Brain Barrier Disruption and Post-Stroke Cognitive Decline
Recruiting · NCT05556395 · Observational (researchers observe without assigning treatment) · Lead sponsor: Johns Hopkins University
View the official record on ClinicalTrials.gov →What this trial is about
The goal of this study is to gain a better understanding of why some individuals who have suffered a stroke experience post-stroke cognitive decline. Specifically this study is testing whether global disruption of the blood-brain barrier detected at the time of the stroke is informative about the risk of post-stroke cognitive decline over the next 3 years.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Acute ischemic stroke demonstrated on an MRI scan that includes perfusion imaging with an exogenous contrast agent
Exclusion criteria
- Inability to perform telephone-based cognitive assessments
Where it is running
1 location listed across 1 US state.
- Johns Hopkins Hospital - Baltimore, Maryland, United States