Two Different Regimens of Bemiparin as a Thromboprophylaxis in Morbidly Obese Surgical Patients
Recruiting · NCT05569681 · Interventional (participants receive a specific treatment) · Lead sponsor: Hawler Medical University
View the official record on ClinicalTrials.gov →Interventions studied
Bemiparin 3500Bemiparin 5000 IU
What this trial is about
Morbid obesity, is known to be associated with a high risk of VTE and, unfortunately, fixed doses of anticoagulant regimens may not provide optimal VTE prophylaxis in these patients especially after surgery.
Who can take part
Age range
18 Years to 90 Years
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Participants required surgical intervention in: general surgery, gynecology, bariatric surgery
- Moderate, high, and very high risk for venous thromboembolism according to Caprin RAM
- Participant is willing and able to give informed consent for participation in the study.
- BMI ≥40kg/m2
Exclusion criteria
- Having any contraindication to LMWH, such as active bleeding, history of heparin-induced thrombocytopenia , baseline platelet count \<75 × 108/μl, severe renal disease (glomerular filtration rate \<30 ml/minute), severe liver disease, or uncontrolled hypertension (\>200/120 mmHg)
- Known hypersensitivity to unfractionated or LMWHs
- On oral or parenteral anticoagulants within 5 days before surgery
- Severe arterial hypertension
- Unable to comply with the study treatment and/or follow-up
- Receiving prohibited medications
- Pregnancy or lactation mother
Where it is running
1 location listed.
- Hawler Medical university - Erbil, Kurdistan Region, Iraq