LONGitudinal Multi-omics Phenotyping of KIDney Function Alteration
Recruiting · NCT05570929 · Observational (researchers observe without assigning treatment) · Lead sponsor: Charite University, Berlin, Germany
View the official record on ClinicalTrials.gov →What this trial is about
This is a longitudinal observation of kidney function, immune system and gut microbiota before and 24 weeks after a live kidney transplantation conducted in donor and recipient pairs living in the same household. Outcome measures include kidney function, body composition, blood pressure, gut microbiome composition, metabolomics and immune cell states.
Who can take part
Age range
18 Years to 75 Years
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Body-Mass-Index 18,5 - 34,9 kg/m2
- Planned living kidney donation / transplantation
Exclusion criteria
- Clinically relevant heart, lung, liver, and kidney diseases
- Postoperative phase
- Acute infections
- Vegan diet
- Change of body weight of more than 10% in the month prior to study entry
- Known drug or alcohol abuse
Where it is running
1 location listed.
- Experimental and Clinical Research Center - Berlin, Germany