Circuit-Based Deep Brain Stimulation for Parkinson's Disease P1A2&3 Catalyst
Recruiting · NCT05658302 · Observational (researchers observe without assigning treatment) · Lead sponsor: University of Minnesota
View the official record on ClinicalTrials.gov →What this trial is about
This study will help us better understand how the brain works in people with Parkinson's disease (PD). PD is a brain disease that gets worse over time, and affects over 10 million people world-wide. A common treatment for PD is Deep Brain Stimulation (DBS). To improve DBS therapy for PD, we need a deeper understanding of how the different parts of the brain work together in PD, and how this relates to movement and thinking problems that people with PD experience. We may be able to use the results of this study to improve DBS treatments in the future.
Who can take part
Age range
21 Years and older
Sex
Female
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Diagnosis of idiopathic PD
- Surgery at UMN to implant DBS system with directional lead(s) and multiple independent current control IPG is planned as part of routine clinical care
- At least 21 years old
Exclusion criteria
- Other significant neurological disorder
- History of dementia
- Patients with post-operative complications or adverse effects (e.g. ON stimulation dystonias) that affect patient safety or confound the experiment will be excluded from further study
- Pregnant women
- Known radiation exposure within the last year that is determined to be unsafe when compounded with the expected radiation dose from intraoperative fluoroscopy to place ECoG strip
Where it is running
1 location listed across 1 US state.
- University Of Minnesota - Minneapolis, Minnesota, United States