The Effects of Using Different Anesthetics on the Prognosis of Primary Lung Tumors and Its Mechanism of Action
Recruiting · NCT05663242 · Interventional (participants receive a specific treatment)
View the official record on ClinicalTrials.gov →Interventions studied
PropofolSevoflurane
What this trial is about
This is a two-arm, parallel-group randomized clinical trial. Routine perioperative care would be performed in volunteers with primary early lung cancer. The study will enroll approximately 300 volunteers to compare the progression-free or overall survival in patients undergoing video-assisted thoracoscopic surgery (VATS) for primary lung tumors between propofol and sevoflurane for the maintenance of anesthesia.
Who can take part
Age range
20 Years to 80 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Phase 4
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- eighteen to eighty-year-old
- ASA class I-III patients
- Received elective thoracic surgery for primary lung tumors under general anesthesia
Exclusion criteria
- mental disorder
- poor liver function
- pregnant or lactating women
- morbidly obese
- allergy to any of the drugs used in this study
- recurrent tumor or repeat surgery
- biopsy cases
- incomplete outcome-data
- palliative treatment after surgery
- simultaneous treatment of other malignancies
- emergency surgery
- presence of other malignant tumors
- combined propofol and inhalation anesthesia or other anesthetics, such as ketamine or dexmedetomidine
- diagnosed as benign lung tumor, or other metastatic lung tumor
Where it is running
1 location listed.
- Kaohsiung Medical University Chung-Ho Memorial Hospital - Kaohsiung City, Taiwan