Sonographic Diaphragm Function in AECOPD
Recruiting · NCT05671198 · Observational (researchers observe without assigning treatment) · Lead sponsor: Isala
View the official record on ClinicalTrials.gov →Interventions studied
Ultrasound of the diaphragm
What this trial is about
The study will be conducted as a single-center, prospective cohort study. The primary objective of this study is to investigate the responsiveness of sonographic parameters of diaphragm to detect change in Borg score for dyspnea during hospitalisation for AECOPD without respiratory acidosis.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Hospitalisation primarily because of severe acute exacerbation of COPD
- COPD, according to GOLD 2018 definition
- Post-bronchodilator FEV1/FVC \< 0,70 and FEV1% \< 80%pred. within last 5 years
Exclusion criteria
- Respiratory acidosis (pH \< 7.35 ánd PaCO2 \> 6 kPA)
- Need for (non-)invasive ventilation based on other criteria (e.g. severe hypoxia) upon presentation.
- Established diagnosis of diaphragm diaphragm paralysis.
- Inability for diaphragm imaging (e.g. mechanical ventilation, or unable to follow vocal instructions).
- Those not able or unwilling to give written informed consent.
- Pregnant women
Where it is running
1 location listed.
- Isala Klinieken - Zwolle, Overijssel, Netherlands