A Study to Learn About Abrocitinib in Adult Patients With Moderate to Severe Atopic Dermatitis.
Recruiting · NCT05689151 · Observational (researchers observe without assigning treatment) · Lead sponsor: Pfizer
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
The purpose of this study is to learn about the safety and effects of Abrocitinib in the real-life clinical setting given for the treatment of moderate to severe atopic dermatitis. Atopic dermatitis, or AD, is a long-lasting disease that causes inflammation, redness, and irritation of the skin. This study is seeking participant who are older than 18 years with moderate-to-severe chronic AD. Participants must have no underlying medical conditions that prevent them from taking Abrocitinib. All participants in this study will receive Abrocitinib as a tablet once daily. They can take Abrocitinib and use medicated topical treatment for AD at the same time. We will examine the experiences of patients receiving the study medicine. This will help us determine if the study medicine is safe and helps in treating AD. Participants will take part in this study for 24 months. During this time, they will visit the study clinic about 5 times (about 1 time every 4 to 6 months).
Who can take part
Inclusion criteria
- Patients older than 18 years of age at inclusion.
- Patients with clinical diagnosis of moderate-to-severe chronic atopic dermatitis (also referred to as atopic eczema) at inclusion according to the investigator and eligible for abrocitinib according to its marketing approval.
- Patients that have been informed of the study procedures and have signed the consent.
Exclusion criteria
- Patients for whom abrocitinib is contraindicated.
- Patients unable to follow and respect the study procedures and judged inapt to respond to the questions required for the study due to linguistical, psychological, social, or geographical reasons.
- Patients not affiliated to the French social security system.
- Patients deprived of liberty, under guardianship, or unable to provide oral consent.
- Patients participating in a clinical study assessing a medicinal treatment (patients can participate in registries and observatories).
Where it is running
30 locations listed.
- CHU Besancon - Hopital Jean Minjoz - Besançon, France
- Polyclinique Reims Bezannes - Bezannes, France
- Chu Bordeaux Hopital Saint Andre - Bordeaux, France
- CHU Brest Hopital Morvan - Brest, France
- CHU de Caen - Caen, France
- Ch de Calais - Calais, France
- Ch William Morey - Chalon-sur-Saône, France
- CHU Clermont Ferrand - Hopital Gabriel Montpied - Clermont-Ferrand, France
- Chu Estaing - Clermont-Ferrand, France
- Hopital Henri Mondor - Créteil, France
- Chu Dijon - Dijon, France
- Hopital Franco Britannique - Levallois-Perret, France
- Hopital Claude Huriez - Lille, France
- CH de Martigues - Martigues, France
- CHU Montpellier - Montpellier, France
- Hopital Emile Muller - Mulhouse, France
- Hopital Hotel Dieu - Nantes, France
- Hopital Cochin - Paris, France
- Hopital Tenon - Paris, France
- Hopital Saint Louis (APHP) - Service Hematologic Senior - Paris, France
- CHU Lyon Sud - Pierre-Bénite, France
- Hopital Pontchaillou - Rennes, France
- Ch de Romans Sur Isere - Romans-sur-Isère, France
- Hopital Charles Nicolle - Rouen, France
- Chi Poissy Saint Germain En Laye - Saint-Germain-en-Laye, France
- Hopital Bégin - Saint-Mandé, France
- Hopital Larrey - Toulouse, France
- Ch de Valenciennes - Valenciennes, France
- CHU Nancy - Vandœuvre-lès-Nancy, France
- CHU Amiens-Picardie - Site Nord - Amiens, Somme, France