Laparoscopic Versus Open Right Colectomy for Right Colon Cancer
Recruiting · NCT05713903 · Interventional (participants receive a specific treatment) · Lead sponsor: Larissa University Hospital
View the official record on ClinicalTrials.gov →Interventions studied
Laparoscopic right colectomyOpen right colectomy
What this trial is about
The purpose of this research protocol is to compare open versus laparoscopic right colectomy (according to the CME technique of complete mesocolic excision) for right colon cancer. This study will be designed as a prospective randomized controlled trial. The comparison of the two techniques will include endpoints regarding the quality characteristics of the specimens and the oncological results. In addition, the effectiveness of the two methods will be evaluated in terms of the early and late postoperative period.
Who can take part
Age range
18 Years to 90 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Histologically confirmed right colon cancer (cecum, ascending colon, hepatic flexure)
- Surgical resection based on the CME principles
- Patient 18 to 90 years old
- American Society of Anesthesiologists score ≤III
- Τ≤3
- Elective operation
- Signed informed consent of the patient
Exclusion criteria
- Non elective operation (hemorrhage, perforation, obstruction)
- Locally advanced disease (T4)
- Distant metastases (Stage IV)
- American Society of Anesthesiologists ≥IV
- Previous laparotomy
- BMI \>35 kg/m2
- Active sepsis or systemic infection
- Untreated physical and mental disability
- Pregnancy or breast-feeding
- Lack of compliance with the protocol process
- Non-granting of signed informed consent
Where it is running
1 location listed.
- Department of Surgery, University Hospital of Larissa - Larissa, Greece