Functional Pulmonary Capillary Surface Area in BPA for CTEPH
Recruiting · NCT05719415 · Interventional (participants receive a specific treatment) · Lead sponsor: Jewish General Hospital
View the official record on ClinicalTrials.gov →Interventions studied
Measurement of pulmonary functional capillary surface area
What this trial is about
Chronic thromboembolic pulmonary hypertension \[CTEPH\] is caused by pulmonary emboli that have enlarged in pulmonary arteries and have become organized into the vessel wall. Many patients with CTEPH are treated with balloon pulmonary angioplasty \[BPA\] which mechanically opens the narrow pulmonary arteries. It is unclear how much downstream functional pulmonary capillary surface area \[FCSA\] is recovered during BPA. The investigators plan to measure FCSAIn CTEPH patients, before and after a session of BPA.
Who can take part
Age range
18 Years to 75 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- All patients eligible for balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension
Exclusion criteria
- Treatment with angiotensin-converting enzyme inhibitors or angiotensin receptor blockers,
- Presence of patent foramen ovale
Where it is running
1 location listed.
- David Langleben - Montreal, Quebec, Canada