Histopathological Analysis of Renal Biopsies With Dynamic Full-field Optical Coherence Tomography, a Comparison to Conventional Histopathological Findings for the Diagnosis of Either Acute Kidney Injury or Chronic Kidney Disease in Routine Practices (NEPHROCT)
Recruiting · NCT05728216 · Observational (researchers observe without assigning treatment) · Lead sponsor: Centre Hospitalier William Morey - Chalon sur Saône
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
Kidney biopsy play a key role for the investigation of either acute kidney injury or chronic kidney disease. Despite possible complications due to the invasive nature of the biopsy, such procedure is still essential in a number of clinical situations to improve the diagnosis specificity of kidney disease, better inform about its prognosis and guide the management of a future treatment. Pursuing the idea to improve both performance and rapidity associated with the histopathological analysis of kidney biopsy, with a possible recourse to artificial intelligence-based renal pathology, the present study intends to assess the impact of direct histopathological examination of kidney biopsy with dynamic full-field optical coherence tomography in routine practices for the diagnosis of either acute kidney injury or chronic kidney disease.
Who can take part
Inclusion criteria
- patients \> 18 years of age with suspected acute kidney injury requiring biopsy in the nephrology department
- patients \> 18 years of age with suspected chronic kidney disease requiring biopsy in the nephrology department
Exclusion criteria
- inability to perform dynamic full-field optical coherence tomography observation at the moment of kidney biopsy
Where it is running
1 location listed.
- Centre Hospitalier William Morey - Chalon sur Saône - Chalon-sur-Saône, Saône-et-Loire, France