Predicting Responsiveness in Oncology Patients Based on Host Response Evaluation During Anti Cancer Treatments, Using Multiomics
Recruiting · NCT05736029 · Observational (researchers observe without assigning treatment)
View the official record on ClinicalTrials.gov →Interventions studied
blood, stool and tissue samples collection
What this trial is about
The goal of this exploratory study is understand the mechanisms of response to immunotherapy in Non-Small Cell Lung Cancer patients. The investigators are going to search for correlation between specific biological features and response to immunotherapy, and to use those associations for developing an algorithm enabling to identify patients that could benefit from the immune check inhibitor based anti cancer treatment. Patients will provide biological samples before and during their treatment, and clinical data will be collected.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Provision of informed consent prior to any study-specific procedures.
- Male or female aged at least 18 years.
- ECOG PS - 0/1-2.
Exclusion criteria
- Any concurrent and/or other active malignancy that has required systemic treatment within 2 years of first dose of treatment.
- Generalized impairment or mental incompetence that would render the patient unable to understand his/her participation in the study.
Where it is running
1 location listed across 1 US state.
- Baylor Scott and White Research Institute - Dallas, Texas, United States