Genetic Predisposition Testing Program for Pancreatic Neuroendocrine Neoplasms
Recruiting · NCT05746182 · Observational (researchers observe without assigning treatment) · Lead sponsor: University of California, San Francisco
View the official record on ClinicalTrials.gov →Interventions studied
Hereditary Cancer Panel
What this trial is about
This is a prospective observational multi-center pilot study of germline testing for participants receiving care at University of California participating locations with a new or existing diagnosis of Pancreatic Neuroendocrine Neoplasms (PanNEN). This protocol is an extension of existing Genetic Testing Station efforts at University of California, San Francisco (UCSF)
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Histologically confirmed PanNEN.
- a. The diagnostic biopsy may have been taken from any site (primary or metastatic).
- New and existing PanNEN participants will be eligible (any grade, any stage, any age \> 18 years).
- Participants willing and able to comply with the study procedures.
Exclusion criteria
- Inability to provide informed consent.
- For participants who have not had prior testing with a dedicated germline pane of at least 80 genes:
- Inability to speak/read a language supported by the germline testing station (GTS). The supported languages currently include English, Korean, Japanese, Vietnamese, Russian, Tagalog, Farsi, Spanish, Cantonese, Mandarin, and Arabic).
- Active hematologic malignancy.
- History of allogenic bone marrow transplant or stem cell transplant.
Where it is running
3 locations listed across 1 US state.
- University of California, Los Angeles - Los Angeles, California, United States
- Univeristy of California, San Diego - San Diego, California, United States
- University of California, San Francisco - San Francisco, California, United States