The HELPP Score: A Pretreatment Score to Predict Survival in Pancreatic Cancer
Recruiting · NCT05752812 · Observational (researchers observe without assigning treatment) · Lead sponsor: Medical University of Vienna
View the official record on ClinicalTrials.gov →What this trial is about
The goal of this observational study is to validate a pretreatment prognostic score (Heidelberg Prognostic Pancreatic Cancer Score - HELPP) in patients with pancreatic ductal adenocarcinoma. The main questions it aims to answer are: * Is the HELPP score able to predict median overall survival in a prospective multi-institutional cohort of patients with pretherapeutic localized non-metastatic pancreatic cancer? * Is the HELPP score able to predict median recurrence-free survival and patterns of recurrence after resection of pancreatic cancer?
Who can take part
Age range
18 Years to 99 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- ≥18 years old
- fit to undergo elective pancreatic resection or palliative therapy
- localized non-metastatic pancreatic ductal adenocarcinoma
- informed consent provided
Exclusion criteria
- patients with a diagnosis other than pancreatic ductal adenocarcinoma on histopathology
- missing informed consent
- missing mandatory pretreatment laboratory values
- missing mandatory pretreatment clinicopathologic data
- patients receiving surgery for peripancreatic cancer
- incomplete follow-up records
- follow-up \< 24 months
- pregnancy
Where it is running
1 location listed.
- Department of General Surgery, Division of Visceral Surgery, Medical University of Vienna - Vienna, Austria