Type 2 Diabetes, Obesity and Cortisol Excess
Recruiting · NCT05759637 · Observational (researchers observe without assigning treatment) · Lead sponsor: Istituto Auxologico Italiano
View the official record on ClinicalTrials.gov →Interventions studied
1mg DST
What this trial is about
The present observational cross-sectional study is aimed to assess: the hidden hypercortisolism (HidHyCo) prevalence in a sample of Type 2 diabetes (T2D) patients and the clinical characteristics more frequently associated with the HidHyCo presence and the HidHyCo prevalence in an adequate sample of obese patients without T2D and the clinical characteristics more frequently associated with the HidHyCo presence.
Who can take part
Age range
18 Years to 75 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- patients with T2D and Obesity
Exclusion criteria
- pregnancy/breast feeding,
- sleep apnea,
- prepuberal onset of hypertension, hormonal hypersecreting adrenal mass,
- symptoms of hypercortisolism;
- already known secondary hypertension;
- conditions associated with increased hypothalamic-pituitary-adrenal (HPA) axis activity, -severe autoimmune/rheumatologic and hematologic diseases, alcoholism, kidney disease (glomerular filtration rate \<60)
- drugs influencing the HPA axis activity. For inclusion in Group 2 the presence of T2D will be an exclusion criteria
Where it is running
5 locations listed.
- Istituto Auxologico Italiano - Milan, Italy
- Niguarda Hospital - Milan, Italy
- Campus Bio-Medico University - Roma, Italy
- University of Siena - Siena, Italy
- Azienda Ospedaliero Universitaria, Santa Maria della Misericordia di Udine - Udine, Italy