Screening for Lung Cancer in Subjects With Family History of Lung Cancer
Recruiting · NCT05762731 · Observational (researchers observe without assigning treatment)
View the official record on ClinicalTrials.gov →Interventions studied
Low dose CT thorax
What this trial is about
Lung cancer can be detected via screening of high-risk individuals, i.e current or ex-heavy smokers, with low-dose computer tomography (LDCT) of thorax. The National Lung Screening Trial in US and the NELSON trial in Europe demonstrated reduction in lung cancer mortality with LDCT screening for lung cancer. In Hong Kong, however, there is a prominence of female never-smokers with lung cancer. There is no identifiable risk factors for non-smokers with lung cancer except family history of lung cancer. The hypothesis is that lung cancer screening for subjects with family history of lung cancer, can detect early lung cancer.
Who can take part
Age range
50 Years to 75 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Age 50-75, men or women, smokers or non-smokers
- Being first degree relatives (Siblings, children, and parents) of lung cancer subjects
- Having no known lung cancer before
Exclusion criteria
- Non-Chinese
- Mentally incompetent to give informed consent
Where it is running
1 location listed.
- University of Hong Kong - Hong Kong, Hong Kong, Hong Kong