The Effects of fNIRS-based Neurofeedback Training on Balance and Gait in Parkinson's Disease
Recruiting · NCT05800470 · Interventional (participants receive a specific treatment) · Lead sponsor: National Yang Ming Chiao Tung University
View the official record on ClinicalTrials.gov →Interventions studied
Kinesthetic motor imageryMotor trainingfNIRS-based neurofeedback with motor imagery
What this trial is about
A cross-sectional study (part 1) aims to investigate the influence of fatigue on the MI ability in PD compared to healthy controls. A randomized controlled trial (part 2) aims to compare the effect of fNIRS-based NFB-MI on balance and gait performance versus MI only in people with PD.
Who can take part
Age range
40 Years to 85 Years
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- for PD:
- diagnosis of idiopathic PD by neurologist with Hoehn and Yahr stage \< 4;
- stable medical condition;
- capability of walking independently without walking devices.
Exclusion criteria
- cognitive impairment indicated by MMSE score \< 24;
- motor imagery ability indicated by KVIQ score \< 25;
- unable recognize 26 letters in the English alphabet
- history of diseases or conditions known to interfere with participating this study (e.g. epilepsy, metal implants in the brain, or deep brain stimulation);
- diagnosis of any other neurological disease or psychiatric disorder (e.g. stroke, anxiety disorder, or depression);
- using central nervous system medications other than for PD, e.g. antiepileptic drugs in recent 3 months.
- Part 2
- Inclusion Criteria:
- aged 40-85 y/o;
- diagnosis of idiopathic PD by neurologist with Hoehn and Yahr stage \< 4;
- stable medical condition;
- capability of walking independently for 10 minutes, which is the time needed for imagery walking training in order to eliminate the possible influence of physical fatigue.
- Exclusion Criteria:
- cognitive impairment indicated by MMSE score \< 24;
- history of diseases or conditions known to interfere with participating this study (e.g. epilepsy, metal implants in the brain, or deep brain stimulation);
- diagnosis of any other neurological disease or psychiatric disorder (e.g. stroke, anxiety disorder, or depression);
- using central nervous system medications other than for PD, e.g. antiepileptic drugs in recent 3 months.
Where it is running
1 location listed.
- National Yang Ming Chiao Tung University - Taipei, None Selected, Taiwan