Investigating Neural Biomarkers for Gait in Parkinson's Patients
Recruiting · NCT05820074 · Observational (researchers observe without assigning treatment) · Lead sponsor: Swiss Federal Institute of Technology
View the official record on ClinicalTrials.gov →Interventions studied
Movement Parameter RecordingNeural Activity RecordingNeuromodulation
What this trial is about
This observational study's main goal is to learn more about the neural mechanisms during movement in Parkinson's disease. Furthermore, it aims to inspire personalised treatment options. Participants will undergo a protocol that involves walking and gait-related motor tasks, such as seated stepping. During the protocol, brain activity will be recorded.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- All participants
- must have given informed consent as documented by signature
- agree to comply with the study procedures
- Healthy control group
- no neurological, orthopedic, or rheumatologic disease history
- no identified sensory impairment.
- no epilepsy and self-diagnosed acute or chronic psychiatric disorders
- Parkinson's Patients
- non-tremor dominant idiopathic PD patients
- presence of postural instability (UPDRS \>1 for postural instability \[17\]), gait disturbance, and absence of other causes of reduced balance
- Implanted with Percept™ PC neurostimulator
- Able to be in the stimulation OFF
Exclusion criteria
- Relevant cognitive impairment, with a score on Montréal Cognitive Assessment (MoCA) \< 20
- History of physical or neurological condition that interferes with study procedures
- Social and/or personal circumstances interfering with the ability to come to the session
Where it is running
1 location listed.
- Cereneo - Vitznau, Canton of Lucerne, Switzerland