HIIT Effects on Cardiometabolic Health

Recruiting · NCT05838950 · Interventional (participants receive a specific treatment) · Lead sponsor: Syracuse University

View the official record on ClinicalTrials.gov →

Obesity

Interventions studied

high-intensity interval training intervention

What this trial is about

The primary aim of this randomized clinical trial is to compare the effects of three different HIIT protocols and a control group on cardiometabolic health in young adults with obesity. Participants will be randomly assigned to one of the following three groups, with each having varying work-to-rest ratios: 1) HIIT-A, 2) HIIT-B, 3) HIIT-C, and 4) control group. HIIT-A, HIIT-B, and HIIT-C groups will participate in six sessions of a running based HIIT program over a 2-week training period. Pre-clinical markers of cardiovascular disease, blood lipids and fasting glucose will be measured at the following three time points: baseline, post-intervention, and 2 weeks after the training cessation (i.e., measure for detraining effect). All measurements will be performed three days before the training program and three days after the intervention to avoid the effect of the last training session. Afterwards, the detraining test will be measured 2 weeks post intervention.

Who can take part

Age range

18 Years to 25 Years

Sex

All (male and female)

Healthy volunteers

No - a diagnosis or condition is required

Phase

Not applicable (e.g. observational or device study)

Study type

Interventional (participants receive a specific treatment)

Inclusion criteria

Young adults with obesity (Age 18 to 25 years old, BMI ≥ 30 kg/m2).

Exclusion criteria

Syndromic obesity; 1) Any clinical symptoms including cognitive delay, 2) abnormalities in body structure(s), 3) organ-specific abnormalities (kidney, liver failure, excessive eating, and/or other signs of hypothalamic dysfunction such as fatigue, weakness and/or lack of interest in activities.
Taking weight loss medication(s)
Currently enrolled (or within previous 6 months) in a weight loss program;
An underlying disease/medications (steroids, second generation psychotropic agents, hormonal contraception, statins, antihypertensive and antidiabetic medications) that could influence carbohydrate or lipid metabolism.
Presence of cardiac pacemaker.
Current or anticipated participation in another research that would interfere with any of the outcomes.
Current or anticipated pregnancy.

Where it is running

1 location listed across 1 US state.

Women's Building - Syracuse, New York, United States

Read the full protocol, contacts and eligibility on ClinicalTrials.gov →