Coronary Flow During Rapid Heart Rates
Recruiting · NCT05841199 · Observational (researchers observe without assigning treatment) · Lead sponsor: Imperial College London
View the official record on ClinicalTrials.gov →Interventions studied
Pressure and flow measurement during simulated VT
What this trial is about
The goal of this observational study is to learn about the factors which determine how well ventricular tachycardia (VT) is tolerated. The main questions it aims to answer are: 1. What impact does coronary artery disease have on the ability for a patient to tolerate VT? 2. Does treatment of coronary artery disease with stents improve the tolerability of VT? Participants who are undergoing a clinically indicated coronary angiogram or coronary angioplasty procedure will have measurements of blood pressure, coronary pressure and coronary flow made during pacing at a range of heart rates.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Able to give valid consent
- Referred for coronary angiography or coronary angioplasty
- Suitable for percutaneous physiological interrogation and PCI when clinically indicated
Exclusion criteria
- Unable to give valid consent
- Pregnant or breastfeeding women
- Unstable coronary artery disease (acute coronary syndrome)
- Severe multivessel coronary artery disease suitable for coronary artery bypass grafting
- Severe heart valve disease
- Severe (NYHA IV) heart failure
Where it is running
1 location listed.
- Imperial College NHS Foundation Trust - London, United Kingdom