South Africa Smoking Cessation and Engagement in HIV/TB Care Care
Recruiting · NCT05842161 · Interventional (participants receive a specific treatment) · Lead sponsor: Massachusetts General Hospital
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
The purpose of this study is to integrate elements from existing interventions developed by our team into a single intervention (QUIT-AD), designed to improve smoking cessation and favorable HIV/TB treatment outcomes among individuals with HIV and/or TB in Cape Town, South Africa. If feasibility, acceptability, and preliminary efficacy are demonstrated, the intervention will be ready for large-scale effectiveness/implementation testing. This program will has the potential to dramatically improve public health by increasing the smoking quit rate and facilitating favorable HIV/TB treatment outcomes among patients with HIV and/or TB in resource limited South African settings.
Who can take part
Inclusion criteria
- Aged 18 or older
- Willing and able to provide written informed consent
- Living with HIV, confirmed via medical record, and on antiretroviral therapy (ART) AND/OR within 1 month of initiating or reinitiating TB treatment; positive GeneXpert test or sputum culture
- Daily smoker operationalized as \> 5 cigarettes per day, (6) Motivation (\> 5/10) to quit smoking or \> 24 hour quit past yr
Exclusion criteria
- Habitual use of other tobacco products
- Current interfering untreated/unstable mental health condition (e.g., psychosis, bipolar dx)
- Current use of non-study pharmacotherapy for smoking cessation,
- Cognitive Behavioral Therapy for smoking cessation initiated within the past year,
- Diagnosed with extra-pulmonary or drug resistant (MDR or XDR) TB based upon chart review
Where it is running
1 location listed.
- University of Cape Town - Rondebosch, South Africa