A Multi-domain Lifestyle Intervention Among Aged Community-residents in Zhejiang, China
Recruiting · NCT05886114 · Interventional (participants receive a specific treatment) · Lead sponsor: Zhejiang University
View the official record on ClinicalTrials.gov →Interventions studied
Self-Guided InterventionStructured Multi-domain Intervention
What this trial is about
A study conducted in Finland discovered that a multidomain intervention, consisting of physical activity, nutritional guidance, cognitive training, social activities, and management of vascular risk factors, effectively decelerated cognitive decline in healthy older adults who were at an increased risk of cognitive decline. The HERITAGE study is a 2-year clustered randomized controlled trial (clustered-RCT) that explores the efficacy of a multidomain intervention among 1200 elderly residents with a higher risk of cognitive decline and dementia in Zhejiang Province, China
Who can take part
Age range
60 Years to 80 Years
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- At risk of cognitive decline: cognitive performance at the mean level or slightly lower than expected for age with no dementia (AD8\>=3 and/or 5-min MoCA \>, \< 11)
- Free of physical disabilities that preclude participation in the study
- Willing to complete all study-related activities for 24 months
- Willing to be randomized to either lifestyle intervention group
Exclusion criteria
- Diagnosed dementia patients
- Diagnosed major depression or other neuropsychological diseases
- Malignant diseases
- Symptomatic cardiovascular disease
- Revascularization within one year
- Severe loss of vision, hearing or communicative ability
Where it is running
1 location listed.
- School of Public Health and The Second Affiliated Hospital of School of Medicine, Zhejiang University, Hangzhou, China - Hangzhou, Zhejiang, China