Mesenchymal Stem Cells Treatment for AIDS Patients at Late Stage
Recruiting · NCT05939167 · Interventional (participants receive a specific treatment) · Lead sponsor: Cell Energy Life Sciences Group Co. LTD
View the official record on ClinicalTrials.gov →Interventions studied
mesenchymal stem cellsaline
What this trial is about
The goal of this study is to conduct a prospective, double-blind, randomized placebo-controlled clinical trial to investigate the safety and efficacy of mesenchymal stem cells treatment for AIDS patients at late stage.
Who can take part
Age range
18 Years to 65 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Phase 1, Phase 2
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Confirmed HIV infection, aged 18-65, both genders
- CD4+T count less than 500 cells/ul at baseline.
- No serious AIDS related events. 3. could understand and sign the informed consent form and comply with the requirements of this study.
- \. agree not to participate in other studies and not to receive other immunotherapies during the period of participation in this study
Exclusion criteria
- have HBV/HCV/HDV/HEV infection, and the virological test is positive.
- The viral load for CMV and EBV is more than 1000 copies/ML.
- have HIV-2 infection.
- have serious complications in organs including renal, circulatory, respiratory, digestive, endocrine, neural and immunological diseases and tumors.
- received treatment of hormones or other immunosuppressive drugs for a long time.
- with serious AIDS related or unrelated events.
- received immunosuppressive drugs or systemic cytotoxic drugs for more than 3 months before recruiting
- have poor compliance during treatment.
- drug addiction within 6 months, or the urine drug test is positive
- participate in other clinical trials currently
- pregnant, breastfeeding, or have fertility requirements.
- unable or unwilling to provide informed consents, or unable to comply with research requirements.
- Other serious situations that may hinder clinical trials.
Where it is running
4 locations listed.
- Beijing 302 Hospital - Beijing, China
- Beijing YouAn Hospital - Beijing, China
- Shenzhen Third People's Hospital - Shenzhen, China
- The Fifth Hospital of Shijiazhuang - Shijiazhuang, China