Trial to Reduce Antimicrobial Use in Nursing Home Residents With Alzheimer's Disease and Other Dementias 2.0
Recruiting · NCT05950607 · Interventional (participants receive a specific treatment) · Lead sponsor: Hebrew SeniorLife
View the official record on ClinicalTrials.gov →Interventions studied
TRAIN AD 2.0
What this trial is about
The goal of this pragmatic cluster randomized clinical trial is to compare management of suspected infection in nursing home residents with dementia The main questions it aims to answer whether residents with dementia in nursing homes randomized to use a multicomponent intervention to optimize suspected infection management ( versus usual care) use less antibiotics and fewer burdensome interventions.
Who can take part
Age range
60 Years to 106 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Age \> 60
- A diagnosis of dementia (any type)
- Cognitive Functional Scale (CFS) \> 1
- NH length of stay \>90 days
- The CFS score categorizes cognitive impairment status based on data in the electronic health record into: 1. None, 2. Mild, 3. Moderate, and 4. Severe (advanced). For the primary outcome, the analysis will be restricted to residents with a CFS score of 3 or 4.
Exclusion criteria
- Less than 60 years of age
- Living in nursing home for less than 90 days
- Does not have diagnosis of dementia
- Does not meet CFS \>1 score
Where it is running
1 location listed across 1 US state.
- Hebrew SeniorLife - Boston, Massachusetts, United States