Cohort Study of Chronic Heart Failure
Recruiting · NCT05960890 · Interventional (participants receive a specific treatment) · Lead sponsor: Jiangsu Taizhou People's Hospital
View the official record on ClinicalTrials.gov →Interventions studied
Remote monitoring assisted by community physicians
What this trial is about
The goal of this observational study is to learn about the influencing factors of chronic heart failure prognosis in heart failure patients. The main question it aims to answer is that what are the influencing factors of clinical outcomes in chronic heart failure. Participants will be collected multiple omics data such as phenotype group, environmental exposure group, intestinal microbiome, genome, metabolome, and noninvasive biomarkers.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Age ≥18 years;
- Fulfill at least one of the following criteria：①History of chronic heart failure;②New-onset heart failure with LVEF \<50%；③New-onset heart failure with LVEF≧50%，E/e'≧15 and BNP\>400 pg/mL/NT-proBNP(\<50 years, \>450 pg/mL; 50\~75 years, \>900 pg/mL; \>75 years, \>1800 pg/mL)
- Etiology: dilated cardiomyopathy, hypertensive heart disease, ischaemic cardiomyopathy, Non-severe valvular heart disease；
- Primary post-discharge therapy: oral medication;
- Sign the informed consent form.
Exclusion criteria
- Patients with renal failure (Ccr\<30ml/min) or patients on dialysis therapy;
- Various correctable secondary causes of cardiac insufficiency including hyperthyroid heart disease, anaemic heart disease, uncorrected congenital heart disease; severe valvular heart disease (including severe stenosis or closure of organic aortic and mitral valves);
- Patients with indications for pacemaker implantation but have not received a pacemaker implant;
- Patients with chronic obstructive pulmonary disease accompanied by type II respiratory failure.
- Patients who cannot understand and sign an informed consent form.
- Patients with mental illness, pregnant women, and other special populations.
Where it is running
1 location listed.
- Taizhou People's Hospital affiliated to Nanjing Medical University - Taizhou, Jiangsu, China