Passive Heat Therapy for People With COPD
Recruiting · NCT05962164 · Interventional (participants receive a specific treatment) · Lead sponsor: University of British Columbia
View the official record on ClinicalTrials.gov →Interventions studied
Passive Heat TherapySham Immersion
What this trial is about
People with Chronic Obstructive Pulmonary Disease (COPD) often develop high blood pressure and heart disease due to their sedentary lifestyle and difficulty exercising. The investigators will test if heating can mimic the health benefits of exercise by monitoring the increase in leg blood-flow using ultrasound during a 45-minute hot-water footbath. The patients will then undergo 6-weeks of hot-water footbaths to examine whether the changes to blood-flow lead to improvements in blood pressure and other indicators of heart disease risk.
Who can take part
Age range
40 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Non-smoking individuals
- \>40 years of age
- Stable (exacerbation free for \>6 weeks), moderate-to-severe COPD (post bronchodilator FEV1/FVC \<lower limit of normal and FEV1 z-score \<2.51)
Exclusion criteria
- Performing structured exercise training (i.e. pulmonary rehabilitation)
- Have advanced cardiac or cerebrovascular disease (i.e. a history of heart failure, previous stroke or myocardial infarction)
- Have uncontrolled hypertension (\>160/95 mmHg at rest)
- Have hypotension (\<110/60 mmHg)
- Are taking Beta Blockers
- Regularly (\>1/week) have hot baths (\>30 min) or use a hot tub or sauna.
- Exclusion Criteria for exercise outcomes:
- Have resting blood pressure \> 150/95 mmHg
- On supplemental oxygen for hypoxemia.
- Musculoskeletal pain that limits their ability to perform stationary cycling.
Where it is running
1 location listed.
- University of British Columbia - Kelowna, British Columbia, Canada