Ethanol Sclerotherapy Prior to ART
Recruiting · NCT05962775 · Interventional (participants receive a specific treatment) · Lead sponsor: Ankara University
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
The goal of this randomized controlled trial is to assess the impact of ethanol sclerotherapy on ART cycle outcomes. The main questions it aims to answer are: 1. Does ethanol sclerotherapy before ART cycle has any impact on cumulative live birth rate in patients with endometrioma? 2. Does ethanol sclerotherapy improve chronic pelvic pain, dysmenorrhea, complications during oocyte retrieval, response to ovarian stimulation (number of mature oocytes retrieved), and pregnancy loss rates? Infertile patients with endometrioma between 4-10 cm who are scheduled for ART within 2 cycles will be randomized to ethanol sclerotherapy or no intervention.
Who can take part
Inclusion criteria
- AMH\>0.3 ng/ml
- unilateral/bilateral endometrioma
- Endometrioma diameter 40-100 mm
Exclusion criteria
- 3 or more IVF/embryo transfer failure
- Menstrual cycle abnormalities
- Male Factor infertility
- Presence of uterine fibroids
- Presence of hydrosalpinx
- Presence of uterine abnormalities
- Suspicion of malignancy according to International Ovarian Tumor Analysis criteria
Where it is running
3 locations listed.
- Başkent University Adana IVF Center - Adana, Turkey (Türkiye)
- Ankara University School of Medicine, Department of Obstetrics and Gynecology - Ankara, Turkey (Türkiye)
- Bahçeci IVF Clinic - Istanbul, Turkey (Türkiye)