Observational SIR-Spheres Study for the Treatment of Unresectable Liver Tumors (SIRtain Registry)
Recruiting · NCT05967143 · Observational (researchers observe without assigning treatment) · Lead sponsor: Sirtex Medical
View the official record on ClinicalTrials.gov →Interventions studied
SIRT
What this trial is about
This registry seeks to prospectively gather a large repository of comprehensive observational data reflecting routine use of SIR-Spheres in patients diagnosed with unresectable HCC or unresectable liver metastases from mCRC refractory to or intolerant to chemotherapy, in order to assess clinical response in a real-world setting and further validate the safe and appropriate use of SIR-Spheres
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Age 18 years or older
- Confirmed diagnosis of:
- Unresectable hepatocellular carcinoma (HCC) Or
- Unresectable liver metastases from colorectal cancer (mCRC) refractory to or intolerant to chemotherapy
- Identified as a candidate for SIR-Spheres treatment as deemed appropriate during the normal course of practice
- Planned to receive SIR-Spheres treatment to the liver for the first time
- Provision of signed patient informed consent
Exclusion criteria
- Prior radiation treatment to the liver
- Caveat:
- Sequential selective internal radiation therapy (SIRT) treatment is allowed
- Patients participating in any interventional clinical trial with an investigational product, device, or procedure
- Need for surrogate consent. Patients who are not able to consent on behalf of themselves are not eligible.
Where it is running
9 locations listed.
- Kings College Hospital - London, United Kingdom
- Hammersmith Hospital - London, United Kingdom
- Hospital General Universitario Gregorio Marañon - Madrid, Spain
- Hospital Clinico Universitario de Valencia - Valencia, Spain
- Hôpital Beaujon - Clichy, Cedex, France
- The Christie Hospital - Manchester, Lancashire, United Kingdom
- Hospital Universitario Puerta de Hierro - Majadahonda - Majadahonda, Madrid, Spain
- Hopital Henri Mondor - Créteil, Paris, France
- Hospices Civils de Lyon HCL Centre Hospitalier Lyon-Sud - Pierre-Bénite, Rhône, France