Coronary Computed Tomography AngioGraphy Prior to Catheter Ablation in Patients With Atrial FIBrillation
Recruiting · NCT05978388 · Interventional (participants receive a specific treatment) · Lead sponsor: Tor Biering-Sørensen
View the official record on ClinicalTrials.gov →Interventions studied
Analysis of coronary CT Angiography and CAC scoring at the time of catheter ablation
What this trial is about
The purpose of this randomized, controlled trial is to investigate whether coronary computed tomography (CT) angiography prior to catheter ablation and derived treatment (medical anti-ischemic and multimodality treatment and/or mechanical revascularization) can improve clinical outcomes in patients with atrial fibrillation undergoing catheter ablation. A sub-study will investigate the effect of different ablation strategies on clinical outcomes in patients with atrial fibrillation undergoing catheter ablation.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Age over 18 years.
- Referral for catheter ablation treatment (excluding AV-junction ablation) for atrial fibrillation (both paroxysmal and persistent atrial fibrillation) at the Department of Cardiology at Gentofte Hospital. Both first ablation and re-ablation treatments are included.
- The ability and willingness to provide written informed consent.
Exclusion criteria
- Known atherosclerotic cardiovascular disease (ASCVD).
- Ongoing treatment with statins.
- Contraindications for coronary CT angiography, e.g. contrast allergy
- Recent coronary CT angiography including CAC-score without positive findings \<3 years prior to screening.
- Any surgical or medical condition, which in the opinion of the investigator, may place the patient at higher risk from his/her participation in the study, or is likely to prevent the patient from complying with the requirements of the study or completing the study.
Where it is running
1 location listed.
- Center for Translational Cardiology and Pragmatic Randomized Trials, Department of Cardiology, Copenhagen University Hospital - Herlev and Gentofte - Hellerup, Capital Region, Denmark