Molecular Markes of Fibrosis of Endometriosis and Their Use in Predicting Disease Severity
Recruiting · NCT06020482 · Observational (researchers observe without assigning treatment) · Lead sponsor: General University Hospital, Prague
View the official record on ClinicalTrials.gov →Interventions studied
Molecular markes of fibrosis of single types of endometriosis and their use in predicting disease severity
What this trial is about
The primary aim of the project is to analyse gene expression in individual types of ectopic endometrium (ovarian endometriosis, peritoneal endometriosis, deep infiltrating endometriosis) and compare it with gene expression in eutopic endometrium. The analysis focuses on the identification of genes with significantly increased expression in each type of ectopic endometrium and comparison of their expression with the degree of disease, ovarian reserve and clinical manifestations of the disease (pain, infertility).
Who can take part
Age range
18 Years to 45 Years
Sex
Female
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- women (18-45 years)
- signed informed consent with the study
- absence of hormonal treatment 3 months before the planned procedure
- Inclusion criteria for group A:
- \- laparoscopically and histologically confirmed endometriosis dg.
- Inclusion criteria for group B:
- patients without endometriosis
- patients who are undergoing an elective laparoscopic or hysteroscopic procedure in our department for another benign indication
- patients with excluded malignant disease
Exclusion criteria
- absence of informed consent
- patients who do not meet the inclusion criteria during surgery
- patient younger than 18 years of age or older than 45 years of age
Where it is running
1 location listed.
- General University Hospital in Prague - Prague, Czechia