Tranexamic Acid Use for Bleeding Prevention in the Surgical Treatment of Metastatic Spinal Tumor in Lung Cancer Patients
Recruiting · NCT06023212 · Interventional (participants receive a specific treatment)
View the official record on ClinicalTrials.gov →Interventions studied
Tranexamic Acidstroke-physiological saline solution (SPSS)
What this trial is about
Massive blood loss occurs in metastatic spinal tumor resection and may cause severe complications. The objective of this study is to investigate whether the use of tranexamic acid will reduce perioperative and postoperative bleeding when compared to those without use of tranexamic acid.
Who can take part
Age range
10 Years to 80 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Phase 1, Phase 2
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Diagnosed as metastatic carcinoma of the thoracolumbar spine
- solitary neoplasm involve only one segment of spine
- patients underwent separation surgery
Exclusion criteria
- coagulation function was abnormal preoperatively
- patients are allergic to tranexamic acid
- neoplasm involve more than one segment of spine
- patients with rich blood supply who need embolization
Where it is running
1 location listed.
- the Second Affiliated Hospital Zhejiang University School of Medicine - Hangzhou, Zhejiang, China