Personalized Accelerated ChEmoRadiation (PACER) for Lung Cancer
Recruiting · NCT06080061 · Interventional (participants receive a specific treatment) · Lead sponsor: Stanford University
View the official record on ClinicalTrials.gov →Interventions studied
Hypofractionated accelerated radiation therapy
What this trial is about
The purpose of this study is to examine the use of hypofractionated accelerated radiation therapy (HART) to treat locally advanced lung cancer. Depending on the location and size of the tumor.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Phase 1
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Histologically or cytologically documented malignancy of the lung including non-small cell lung cancer or small cell lung cancer planned for definitive therapy with fractionated radiation (60-66 Gy) and concurrent systemic therapy
- ECOG performance status of 0-2
- Age ≥ 18 years old
- Ability to understand and the willingness to personally sign the written IRB approved informed consent document
- Estimated life expectancy of 12 weeks or longer
Exclusion criteria
- Contraindication to receiving radiotherapy or systemic therapy as determined by treating radiation and medical oncologist
- Age \< 18 years old
- Tumor directly invading the major pulmonary arteries, aorta, heart or proximal bronchial tree
- Diagnosis of interstitial pulmonary fibrosis
- Previous radiation therapy to the thorax that would result in overlapping high dose radiation fields
Where it is running
2 locations listed across 1 US state.
- Stanford University - Palo Alto, California, United States
- Stanford Cancer Center South Bay - San Jose, California, United States