Efficacy of Songling Xuemaikang Capsules on Grade 1 Hypertension: a Randomized Controlled Trial
Recruiting · NCT06093932 · Interventional (participants receive a specific treatment) · Lead sponsor: Xiyuan Hospital of China Academy of Chinese Medical Sciences
View the official record on ClinicalTrials.gov →Interventions studied
Lifestyle interventionPlaceboSongling Xuemaikang Capsules
What this trial is about
The purpose of this study is: 1. To evaluate the efficacy of Songling Xuemaikang Capsules(SLXMKC) with grade 1 hypertension. 2. To reveal the potiential effects of SLXMKC on vascular function and structure of patients with grade 1 hypertension. 3. To explore the underlying mechanisms of the therapeutic effects of SLXMKC on the intervention of grade 1 hypertension.
Who can take part
Age range
35 Years to 65 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Phase 4
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Age between 35-65 years old, male or female;
- Grade 1 essential hypertension;
- Taking no antihypertensive drugs or taking antihypertensive drugs irregularly in the past ;
- Sign the informed consent;
Exclusion criteria
- Significant liver and kidney dysfunction, ALT and AST upper the twice of normal range, Scr≥2.0mg/dl, eGFR\<60ml/(min·1. 73m2);
- Gastrointestinal diseases, which may affect drug absorption;
- Be allergic to the clinical trial medicine;
- Pregnant or breastfeeding women, men who plan to give birth within half a year;
- Combined with other serious primary diseases or malignant tumors;
- Hyperlipidemia with or without taking lipid-lowering drugs;
- Combined with left ventricular hypertrophy, ABI \< 0.9, CIMT ≥ 0.9mm or atherosclerotic plaque;
- Hypertensive comorbidities (cerebrovascular disease, other cardiovascular diseases, renal disease, peripheral artery disease, retinopathy, diabetes);
- Other serious conditions in which is not fit for the study.
Where it is running
5 locations listed.
- Xiyuan Hospital of China Academy of Chinese Medical Sciences - Beijing, Beijing Municipality, China
- Suzhou Hosptial of Traditional Chinese Medicine - Suzhou, Jiangsu, China
- Affiliated Hospital of Shandong University of Traditional Chinese Medicine - Jinan, Shandong, China
- China Academy of Chinese Medical Sciences Xiyuan Hospital Jining Hospital - Jining, Shandong, China
- China Academy of Chinese Medical Sciences Xiyuan Hospital Shanxi Hospital - Taiyuan, Shanxi, China