Androgens and NAFLD Longitudinal Cohort Study
Recruiting · NCT06124261 · Observational (researchers observe without assigning treatment) · Lead sponsor: University of California, San Francisco
View the official record on ClinicalTrials.gov →What this trial is about
The researchers want to learn how androgens, a type of sex hormone, might affect nonalcoholic fatty liver (NAFLD) in young women over time. NAFLD happens when fat builds up in the liver which can cause damage to the liver such as inflammation or scarring. Young women with a condition called polycystic ovary syndrome (PCOS) have a high risk for NAFLD, and they often have high androgen levels too. So the researchers are recruiting young women with PCOS as well as those without PCOS, and will compare changes in NAFLD over time between young women with and without PCOS. This study is funded by the National Institutes of Health
Who can take part
Inclusion criteria
- Metabolic associated steatohepatitis (MASH) (formerly NASH)
- PCOS
- Non-PCOS
Exclusion criteria
- High levels of alcohol use (more than 7 drinks a week)
- Current pregnancy
- Other causes of hepatic steatosis
- Weight loss of more than 10% body weight in the last 6 months
Where it is running
4 locations listed across 2 US states.
- University of California San Francisco - San Francisco, California, United States
- University of California San Francisco - San Francisco, California, United States
- Duke University - Durham, North Carolina, United States
- Duke University - Durham, North Carolina, United States